Microfluidic lab-on-a-chip systems based on polymers - fabrication and application

被引：69

作者：

Guber, AE ^{[1
]}

Heckele, M

Herrmann, D

Muslija, A

Saile, V

Eichhorn, L

Gietzelt, T

Hoffmann, W

Hauser, PC

Tanyanyiwa, J

Gerlach, A

Gottschlich, N

Knebel, G

机构：

[1] Forschungszentrum Karlsruhe, Inst Mikrostrukturtech, D-76021 Karlsruhe, Germany

[2] Forschungszentrum Karlsruhe, Inst Mikroverfahrenstech, D-76021 Karlsruhe, Germany

[3] Forschungszentrum Karlsruhe, Inst Analyt Instrumentat, D-76021 Karlsruhe, Germany

[4] Univ Basel, Dept Chem, CH-4004 Basel, Switzerland

[5] Greiner Bio One GmbH, D-72636 Frickenhausen, Germany

来源：

CHEMICAL ENGINEERING JOURNAL | 2004年 / 101卷 / 1-3期

关键词：

microfluidic systems; lab-on-a-chip; capillary electrophoresis; CCD technique;

D O I：

10.1016/j.cej.2004.01.016

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

In the future, plastic-based lab-on-a-chip systems will play a crucial role in modem life sciences, e.g. biotechnology and (bio)medical engineering. Presently, nucrofluidic systems for capillary electrophoresis (CE) are being used. They allow for the safe handling of smallest substance volumes in the pL range and their separation into the individual components. From the microtechnical point of view, current R&D activities mainly focus on the development of inexpensive fabrication methods. Low-cost CE systems may be obtained by plastic molding techniques on a polymer basis. First separations of biological fluids and inorganic ion solutions have been performed successfully. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：447 / 453

页数：7

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