A concise enantioselective pathway to carbocyclic nucleoside: Asymmetric synthesis of carbocyclic moiety of carbovir

被引:13
作者
Tanimori, S
Tsubota, M
He, MQ
Nakayama, M
机构
[1] Department of Applied Biochemistry, College of Agriculture, Osaka Prefecture University, Sakai, Osaka 593
关键词
D O I
10.1080/00397919708004098
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
(-)-Trans-4-t-butyldimethylsilyloxymethyl-2-cyclopentenol (13), a key intermediate for the synthesis of (-)-carbovir (15), was synthesized by using enantioselective bicyclic ring construction of chiral alpha-diazo-beta-keto ester 3 catalyzed by rhodium (II) acetate.
引用
收藏
页码:2371 / 2378
页数:8
相关论文
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