Lessons from immuno-oncology: a new era for cancer nanomedicine?

被引：38

作者：

Jiang, Wen ^{[1
]}

Yuan, Hengfeng ^{[2
,3
]}

Chan, Charles K. ^{[4
]}

von Roemeling, Christina A. ^{[3
]}

Yan, Zuoqin ^{[2
]}

Weissman, Irving L. ^{[4
,5
,6
]}

Kim, Betty Y. S. ^{[3
,7
,8
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Radiat Oncol, 1515 Holcombe Blvd, Houston, TX 77030 USA

[2] Fudan Univ, Zhongshan Hosp, Dept Orthoped, 111 Yixueyuan Rd, Shanghai, Peoples R China

[3] Mayo Clin, Coll Med, Dept Neurosurg, 4500 San Pablo Rd, Jacksonville, FL 32224 USA

[4] Stanford Univ, Inst Stem Cell Biol & Regenerat Med, 450 Serra Mall, Palo Alto, CA 94305 USA

[5] Stanford Univ, Dept Pathol, 450 Serra Mall, Palo Alto, CA 94305 USA

[6] Stanford Univ, Dept Dev Biol, 450 Serra Mall, Palo Alto, CA 94305 USA

[7] Mayo Clin, Coll Med, Dept Canc Biol, 4500 San Pablo Rd, Jacksonville, FL 32224 USA

[8] Mayo Clin, Coll Med, Dept Neurosci, 4500 San Pablo Rd, Jacksonville, FL 32224 USA

来源：

NATURE REVIEWS DRUG DISCOVERY | 2017年 / 16卷 / 06期

关键词：

DELIVERY;

D O I：

10.1038/nrd.2017.34

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Despite a decade of intensive preclinical research, the translation of cancer nanomedicine to the clinic has been slow. Here, we discuss how recent lessons learned from the successes with immuno-oncology therapies could be applied to cancer nanomedicine and how this may help to overcome some of the key technical challenges in this field.

引用

页码：369 / 370

页数：2

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