PARP inhibitors in the ovarian cancer therapy

被引：0

作者：

Kruczala, Maksymilian A. ^{[1
]}

Grela-Wojewoda, Aleksandra ^{[1
]}

Cedrych, Ida ^{[1
]}

机构：

[1] Klin Nowotworow Ukladowych & Uogolnionych, Ctr Onkol Inst, Marii Sklodowskiej Curie Oddzial Krakowie, Ul Garncarska 11, PL-31115 Krakow, Poland

来源：

GINEKOLOGIA POLSKA | 2016年 / 87卷 / 02期

关键词：

targeted therapy; ovarian cancer; PARP inhibitors; RANDOMIZED PHASE-2; OLAPARIB; TRIAL;

D O I：

暂无

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Treatment of the malignant ovarian tumors remains a considerable challenge due to various reasons, including lack of effective screening technique, usually asymptomatic early stages of the disease, resulting in advanced stages of the disease at diagnosis, and eventually poor prognosis. Treatment of the relapse remains palliative. New drugs like PARP inhibitors - offer hope for the improvement of treatment outcomes. This review paper presents the current state of knowledge on PARP inhibitors in ovarian cancer therapy.

引用

页码：131 / 134

页数：4

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