The developing synapse: Construction and modulation of synaptic structures and circuits

被引：362
作者：
Cohen-Cory, S [1 ]
机构：
[1] Univ Calif Los Angeles, Dept Psychiat & Biobehav Sci, Mental Retardat Res Ctr, Los Angeles, CA 90095 USA
来源：
SCIENCE | 2002年 / 298卷 / 5594期
关键词：
D O I：
10.1126/science.1075510
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Synapse formation and stabilization in the vertebrate central nervous system is a dynamic process, requiring bi-directional communication between pre- and postsynaptic partners. Numerous mechanisms coordinate where and when synapses are made in the developing brain. This review discusses cellular and activity-dependent mechanisms that control the development of synaptic connectivity.
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页码：770 / 776
页数：7
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