Studies toward Taxuspine X, a potent multidrug-resistance reversing agent, via ring closing metathesis strategy

被引：13

作者：

Renzulli, ML ^{[1
]}

Rocheblave, L ^{[1
]}

Avramova, S ^{[1
]}

Corelli, F ^{[1
]}

Botta, M ^{[1
]}

机构：

[1] Univ Siena, Dipartimanto Farmaco Chim Tecnol, I-53100 Siena, Italy

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 26期

关键词：

taxuspine analogues; synthesis; macrocyclization; ring closing metathesis;

D O I：

10.1016/j.tetlet.2004.04.147

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of bicyclic 3,8-secotaxane diterpenoids, which includes Taxuspine U and X, has been achieved through an approach that involves a ring closing metathesis reaction as key step for the macrocycle formation. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：5155 / 5158

页数：4

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