Venous thrombosis: Prevalence and interaction of risk factors

被引：0
作者：
Rosendaal, FR [1 ]
机构：
[1] Leiden Univ Hosp, Dept Clin Epidemiol, NL-2300 RC Leiden, Netherlands
来源：
HAEMOSTASIS | 1999年 / 29卷
关键词：
gene-gene interaction; gene-environment interaction; selection and interaction; dynamic age-dependent model; factor V Leiden; factor VIII; protein C deficiency;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The key to understanding why certain individuals develop deep vein thrombosis at varying times, despite similar risk facto rs being present, is the realization of the importance of gene-gene and gene-environment interactions between risk factors. The discovery of factor V Leiden and several other coagulation abnormalities, which are now known to be common in the general population, has revolutionized the way in which the aetiology of venous thrombosis is viewed. On the basis of current knowledge, time-dependent models taking account of various forms of interaction have been developed. Copyright (C) 1999 Karger AG, Basel.
引用
收藏
页码：1 / 9
页数：9
相关论文
共 50 条
  • [21] Predicting venous thrombosis in women using a combination of genetic markers and clinical risk factors
    Bruzelius, M.
    Bottai, M.
    Sabater-Lleal, M.
    Strawbridge, R. J.
    Bergendal, A.
    Silveira, A.
    Sundstrom, A.
    Kieler, H.
    Hamsten, A.
    Odeberg, J.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2015, 13 (02) : 219 - 227
  • [22] Thrombophilic risk factors among 16 Lebanese patients with cerebral venous and sinus thrombosis
    Otrock, Zaher K.
    Taher, Ali T.
    Shamseddeen, Wael A.
    Mahfouz, Rami A.
    JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 2008, 26 (01) : 41 - 43
  • [23] Thrombophilic risk factors among 16 Lebanese patients with cerebral venous and sinus thrombosis
    Zaher K. Otrock
    Ali T. Taher
    Wael A. Shamseddeen
    Rami A. Mahfouz
    Journal of Thrombosis and Thrombolysis, 2008, 26 : 41 - 43
  • [24] Interaction between hyperhomocysteinemia, mutated methylenetetrahydrofolatereductase (MTHFR) and inherited thrombophilic factors in recurrent venous thrombosis
    Keijzer, MBAJ
    den Heijer, M
    Blom, HJ
    Bos, GMJ
    Willems, HPJ
    Gerrits, WBJ
    Rosendaal, FR
    THROMBOSIS AND HAEMOSTASIS, 2002, 88 (05) : 723 - 728
  • [25] Interaction between tissue factor pathway inhibitor and factor V levels on the risk of venous thrombosis
    Dahm, A. E. A.
    Bezemer, I. D.
    Sandset, P. M.
    Rosendaal, F. R.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2010, 8 (05) : 1130 - 1132
  • [26] Risk of venous thrombosis in persons with increased body mass index and interactions with other genetic and acquired risk factors
    Ribeiro, D. D.
    Lijfering, W. M.
    Rosendaal, F. R.
    Cannegieter, S. C.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2016, 14 (08) : 1572 - 1578
  • [27] Determination of the Risk Group in Patients with Venous Thrombosis
    Eren, Pinar Ata
    Denizli, Nazim
    Sokmen, H. Mehmet
    Erdem, Solmaz
    Solak, Mustafa
    TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, 2009, 29 (06): : 1430 - 1434
  • [28] Thrombophilia and risk of venous thrombosis in patients with cancer
    Decousus, Herve
    Moulin, Nathalie
    Quenet, Sara
    Bost, Vincent
    Rivron-Guillot, Karine
    Laporte, Silvy
    Mismetti, Patrick
    THROMBOSIS RESEARCH, 2007, 120 : S51 - S61
  • [29] Mesenteric venous thrombosis
    Harnik, Ian G.
    Brandt, Lawrence J.
    VASCULAR MEDICINE, 2010, 15 (05) : 407 - 418
  • [30] Effect of elevated levels of coagulation factors on the risk of venous thrombosis in long-distance travelers
    Kuipers, Saskia
    Cannegieter, Suzanne C.
    Doggen, Carine J. M.
    Rosendaal, Frits R.
    BLOOD, 2009, 113 (09) : 2064 - 2069
12345