Venous thrombosis: Prevalence and interaction of risk factors

被引：0

作者：

Rosendaal, FR ^{[1
]}

机构：

[1] Leiden Univ Hosp, Dept Clin Epidemiol, NL-2300 RC Leiden, Netherlands

来源：

HAEMOSTASIS | 1999年 / 29卷

关键词：

gene-gene interaction; gene-environment interaction; selection and interaction; dynamic age-dependent model; factor V Leiden; factor VIII; protein C deficiency;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The key to understanding why certain individuals develop deep vein thrombosis at varying times, despite similar risk facto rs being present, is the realization of the importance of gene-gene and gene-environment interactions between risk factors. The discovery of factor V Leiden and several other coagulation abnormalities, which are now known to be common in the general population, has revolutionized the way in which the aetiology of venous thrombosis is viewed. On the basis of current knowledge, time-dependent models taking account of various forms of interaction have been developed. Copyright (C) 1999 Karger AG, Basel.

引用

页码：1 / 9

页数：9

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