Antimicrobial and antibiofilm activities of alcoholic extract of olive leaves (olea europaea) against pathogenic bacteria

A long time ago the importance of olive leaf extract was proven in the treatment of many cases that can be caused by viruses, bacteria, fungi and others organisms. And in this study results showed that, all bacteria were resisted to almost antibiotics which used in this study. The antibacterial activity of alcoholic olive leaf extract (OLE) was confirmed with agar well diffusion method and the OLE was had a good antibacterial activity with low concentrations against pathogenic bacteria were used in this study. And MIC, MBC concentrations were showed that OLE had higher concentrations of MIC 30 mg/ml and MBC of 60 mg/ml respectively against Pseudomonas aeruginosa. And lower concentrations of MBC Staphylococcus aureus (MRSA) isolate was sensitive to (OLE) in 15 mg/ml, while MIC was 7.5 mg/ml. The results were showed that all bacteria were used in this study were strong biofilm production, and (OLE) can inhibit biofilm formation in pathogenic bacteria were selected in this study, (p <= 0.05) .except Escherichia coli the OLE did not have activity against biofilm which produced by this bacteria, p value = (0.2).