Solid phase microextraction (SPME)-transmission mode (TM) pushes down detection limits in direct analysis in real time (DART)

被引：92

作者：

Gomez-Rios, German Augusto ^{[1
]}

Pawliszyn, Janusz ^{[1
]}

机构：

[1] Univ Waterloo, Dept Chem, Waterloo, ON N2L 3G1, Canada

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 85期

基金：

加拿大自然科学与工程研究理事会;

关键词：

DESORPTION ELECTROSPRAY-IONIZATION; TANDEM MASS-SPECTROMETRY; PAPER SPRAY; WHOLE-BLOOD; OPEN-AIR; DRUGS; SPOTS; SPME;

D O I：

10.1039/c4cc05301j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new SPME device was developed and applied for quick solventless extraction/enrichment of small molecules from complex matrices. Subsequently, the device was coupled as a transmission mode substrate to DART resulting in limits of detection in the low pg mL(-1) level in less than 3 minutes with reproducibility below 5% RSD.

引用

页码：12937 / 12940

页数：4

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