New access to thiazolo[4,5-d]pyrimidine derivatives

被引：41
作者：
Bakavoli, M. [1 ]
Nikpour, M. [1 ]
Rahimizadeh, M. [1 ]
机构：
[1] Ferdowsi Univ Mashhad, Sch Sci, Dept Chem, Mashhad 917751436, Iran
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2006年 / 43卷 / 05期
关键词：
D O I：
10.1002/jhet.5570430527
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
4-Amino-5-bromo-2-substituted-aminopyrimidines are readily obtained from the newly prepared 5-bromo-2,4-dichloro-6-methylpyrimidine by sequential treatment with ethanolic ammonia and secondary amines. These compounds were successfully reacted with various isothiocyanates in the presence of sodamide in DMF to form the new thiazolo[4,5-d] pyrimidine derivatives.
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页码：1327 / 1329
页数：3
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