Changes in serum cardiac troponin I levels after percutaneous transluminal coronary angioplasty

Objective percutaneous myocardium. To evaluate transluminal the possible effect of coronary ( PTCA) on Methods Serum cTnI and CK-MB were measured in 60 patients with coronary artery disease (CAD) who underwent PTCA before and at the 6th, 12th, 24th, 48th and 72nd hour after the interventional procedure respectively. Results The serum cTnI levels began to increase at 6 hours (9.65 +/- 6.27 mu g/L) in 18 patients, reached the peak levels during 12 - 24 hours (20.43 +/- 11.28 mu g/L, 18.52 +/- 9.52 mu g/L), and returned to normal range till 48 - 72 hours (7.35 +/- 7.62 mu g/L, 5.51 +/- 3.13 mu g/L) after PTCA. The serum cTnI and CK-MB levels were kept normal range pre- and post- PTCA in 30 cases. The levels of cTnI in 12 cases were over baseline either before or after the procedure, while for CK-MB, only in 3 cases were over normal range after PTCA. Compared with normal cTnI group, elevated cTnI levels were related to total inflation times and dilated times (P<0.05). Conclusions PTCA may cause some minor damage in myocardium, serum cTnI level was more sensitive and specific for monitoring myocardial injury.