Peptide-templated gold nanoclusters as a novel label-free biosensor for the detection of protease activity

被引：35
|
作者：
Gu, Yi [1 ]
Wen, Qian [1 ]
Kuang, Yongqing [1 ]
Tang, Lijuan [1 ]
Jiang, Jianhui [1 ]
机构：
[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China
来源：
RSC ADVANCES | 2014年 / 4卷 / 27期
关键词：
ENZYME-ACTIVITY; AU CLUSTERS; NANOPARTICLES; ASSAY;
D O I：
10.1039/c4ra00096j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel label-free fluorescent biosensor platform has been developed for protease activity assay using peptide-templated gold nanoclusters (AuNCs). The biosensor was demonstrated with elastase as the model to have high sensitivity, excellent specificity, simplicity and rapidity.
引用
收藏
页码：13753 / 13756
页数：4
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