Peptide-templated gold nanoclusters as a novel label-free biosensor for the detection of protease activity

被引：37

作者：

Gu, Yi ^{[1
]}

Wen, Qian ^{[1
]}

Kuang, Yongqing ^{[1
]}

Tang, Lijuan ^{[1
]}

Jiang, Jianhui ^{[1
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China

来源：

RSC ADVANCES | 2014年 / 4卷 / 27期

关键词：

ENZYME-ACTIVITY; AU CLUSTERS; NANOPARTICLES; ASSAY;

D O I：

10.1039/c4ra00096j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel label-free fluorescent biosensor platform has been developed for protease activity assay using peptide-templated gold nanoclusters (AuNCs). The biosensor was demonstrated with elastase as the model to have high sensitivity, excellent specificity, simplicity and rapidity.

引用

收藏

页码：13753 / 13756

页数：4

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