What Is XNA?

被引：88

作者：

Chaput, John C. ^{[1
,2
,3
]}

Herdewijn, Piet ^{[4
]}

机构：

[1] Univ Calif Irvine, Dept Pharmaceut Sci, Irvine, CA 92697 USA

[2] Univ Calif Irvine, Dept Chem, Irvine, CA 92717 USA

[3] Univ Calif Irvine, Dept Mol Biol & Biochem, Irvine, CA 92717 USA

[4] Katholieke Univ Leuven, Med Chem, Rega Inst Med Res, Leuven, Belgium

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2019年 / 58卷 / 34期

基金：

美国国家科学基金会;

关键词：

synthetic biology; xeno-nucleic acid; XNA; DNA; STABILITY; TNA;

D O I：

10.1002/anie.201905999

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The term "xeno-nucleic acids", abbreviated XNA, has grown in popularity to the point that it has become a catch-all phrase for almost any unnatural nucleic acid, raising the question: what is XNA and how does it differ from chemically modified DNA?

引用

页码：11570 / 11572

页数：3

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