The role of lymphadenectomy in the management of renal cell carcinoma

被引：11

作者：

Barrisford, Glen W. ^{[1
]}

Gershman, Boris ^{[1
]}

Blute, Michael L., Sr. ^{[1
]}

机构：

[1] Harvard Univ, Massachusetts Gen Hosp, Dept Urol, Sch Med, Boston, MA 02114 USA

来源：

WORLD JOURNAL OF UROLOGY | 2014年 / 32卷 / 03期

关键词：

Renal cell carcinoma; Renal cancer; Lymphadenectomy; Lymph node dissection; LYMPH-NODE DISSECTION; PROSPECTIVE CLINICAL-TRIALS; RADICAL NEPHRECTOMY; STRATIFICATION TOOL; SURGICAL RESECTION; SURVIVAL; CANCER; PROGRESSION; METASTASES; PREDICTION;

D O I：

10.1007/s00345-014-1294-5

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The role of lymphadenectomy in the management of renal cell carcinoma has been established in staging but is less well defined as a therapeutic maneuver. Level one evidence suggests no survival benefit or increased complication rate with lymphadenectomy when performed concurrently with radical nephrectomy. However, several retrospective studies have identified a survival benefit when patients with increased risk of micrometastatic lymph node disease undergo lymphadenectomy. We perform a selective review of the literature and present the historical basis, risk assessment, use and development of nodal templates, and therapeutic benefits associated with the use of lymphadenectomy in the management of renal cell carcinoma.

引用

页码：643 / 649

页数：7

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