Effect of paracetamol in aqueous sodium malonate solutions with reference to volumetric and viscometric measurements

Apparent molar volumes and viscosity B-coefficients for paracetamol in aqueous sodium malonate solutions were determined from solution densities and viscosities measured at T = (298.15 to 318.15) K and at pressure p = 101 kPa as a function of paracetamol concentrations. The standard partial molar volumes (phi(0)(V)) and slopes (S-V(*)) obtained from Masson equation were interpreted in terms of (solute + solvent) and (solute + solute) interactions, respectively. Solution viscosities were analyzed using Jones-Dole equation and the viscosity A and B coefficients discussed in terms of (solute + solute) and (solute + solvent) interactions, respectively. The standard volume of transfer (Delta(t)phi(0)(V)) and viscosity B-coefficients of transfer (Delta B-t) of paracetamol from water to aqueous sodium malonate solutions were derived to understand various interactions in the ternary solutions. The activation parameters of viscous flow for the studied solutions were discussed in terms of transition state theory. The structure making or breaking ability of Paracetamol was discussed in terms of the sign of (d phi(0)(E)/dT)(P). (C) 2016 Elsevier Ltd. All rights reserved.