Hepatic Retransplant What Have We Learned?

被引:22
作者
Kitchens, William H. [1 ]
Yeh, Heidi [2 ]
Markmann, James F. [2 ]
机构
[1] Massachusetts Gen Hosp, Dept Surg, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Dept Surg, Div Transplantat, Boston, MA 02114 USA
关键词
Liver transplant; Retransplant; Risk prediction models; Hepatitis C virus; MELD scores; SINGLE-CENTER EXPERIENCE; LONG-TERM SURVIVAL; LIVER-TRANSPLANT RECIPIENTS; RISK-FACTORS; C-VIRUS; GRAFT FAILURE; PREDICTING SURVIVAL; NATURAL-HISTORY; UNITED-STATES; MELD SCORE;
D O I
10.1016/j.cld.2014.05.010
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Hepatic retransplant is the sole option for survival in many patients suffering hepatic dysfunction after liver transplant, but it is associated with significantly increased hospital costs and inferior outcomes compared to primary transplants. In this review, the indications for both early and late liver retransplant are presented. The controversy regarding retransplant in patients infected with hepatitis C virus is discussed, and the recipient and donor graft characteristics impacting survival following hepatic retransplant are analyzed. With improved risk stratification models to match retransplant candidates with appropriate donor grafts, it is hoped that the clinical outcomes of retransplant will continue to improve.
引用
收藏
页码:731 / +
页数:22
相关论文
共 103 条
[1]   Liver Retransplantation of More Than Two Grafts for Recurrent Failure [J].
Akpinar, Edip ;
Selvaggi, Gennaro ;
Levi, David ;
Moon, Jang ;
Nishida, Seigo ;
Island, Eddie ;
DeFaria, Werviston ;
Pretto, Ernesto ;
Ruiz, Philip ;
Tzakis, Andreas G. .
TRANSPLANTATION, 2009, 88 (07) :884-890
[2]   A Score Predicting Survival After Liver Retransplantation for Hepatitis C Virus Cirrhosis [J].
Andres, Axel ;
Gerstel, Eric ;
Combescure, Christophe ;
Asthana, Sonal ;
Merani, Shaheed ;
Majno, Pietro ;
Berney, Thierry ;
Morel, Philippe ;
Kneteman, Norman ;
Mentha, Gilles ;
Toso, Christian .
TRANSPLANTATION, 2012, 93 (07) :717-722
[3]   Decision for retransplantation of the liver - An experience- and cost-based analysis [J].
Azoulay, D ;
Linhares, MM ;
Huguet, E ;
Delvart, V ;
Castaing, D ;
Adam, R ;
Ichai, P ;
Saliba, F ;
Lemoine, A ;
Samuel, D ;
Bismuth, H .
ANNALS OF SURGERY, 2002, 236 (06) :713-721
[4]   Retransplantation for Donor-Derived Neuroendocrine Tumor [J].
Begum, Rehana ;
Harnois, Denise ;
Satyanarayana, Raj ;
Krishna, Murli ;
Halling, Kevin C. ;
Kim, George P. ;
Nguyen, Justin H. ;
Keaveny, Andrew P. .
LIVER TRANSPLANTATION, 2011, 17 (01) :83-87
[5]   Early Hepatic Artery Thrombosis after Liver Transplantation: A Systematic Review of the Incidence, Outcome and Risk Factors [J].
Bekker, J. ;
Ploem, S. ;
de Jong, K. P. .
AMERICAN JOURNAL OF TRANSPLANTATION, 2009, 9 (04) :746-757
[6]   Have We Changed the Liver Retransplantation Survival? [J].
Bellido, C. B. ;
Martinez, J. M. A. ;
Artacho, G. S. ;
Gomez, L. M. M. ;
Diez-Canedo, J. S. ;
Pulido, L. B. ;
Acevedo, J. M. P. ;
Ruiz, J. P. ;
Bravo, M. A. G. .
TRANSPLANTATION PROCEEDINGS, 2012, 44 (06) :1526-1529
[7]   Severe recurrent hepatitis C after liver retransplantation for hepatitis C virus-related graft cirrhosis [J].
Berenguer, M ;
Prieto, M ;
Palau, A ;
Rayón, J ;
Carrasco, D ;
San Juan, F ;
López-Labrador, FX ;
Moreno, R ;
Mir, J ;
Berenguer, J .
LIVER TRANSPLANTATION, 2003, 9 (03) :228-235
[8]   Natural history of clinically compensated hepatitis C virus-related graft cirrhosis after liver transplantation [J].
Berenguer, M ;
Prieto, M ;
Rayón, JM ;
Mora, J ;
Pastor, M ;
Ortiz, V ;
Carrasco, D ;
San Juan, F ;
Burgueño, MDJ ;
Mir, J ;
Berenguer, J .
HEPATOLOGY, 2000, 32 (04) :852-858
[9]   HCV-related fibrosis progression following liver transplantation:: increase in recent years [J].
Berenguer, M ;
Ferrell, L ;
Watson, J ;
Prieto, M ;
Kim, M ;
Rayón, M ;
Córdoba, J ;
Herola, A ;
Ascher, N ;
Mir, J ;
Berenguer, J ;
Wright, TL .
JOURNAL OF HEPATOLOGY, 2000, 32 (04) :673-684
[10]   Futility and rationing in liver retransplantation: When and how can we say no? [J].
Biggins, Scott W. .
JOURNAL OF HEPATOLOGY, 2012, 56 (06) :1404-1411