Synthesis of novel Schiff bases and azol-β-lactam derivatives starting from morpholine and thiomorpholine and investigation of their antitubercular, antiurease activity, acethylcolinesterase inhibition effect and antioxidant capacity

被引：37

作者：

Cebeci, Yildiz Uygun ^{[1
]}

Bayrak, Hacer ^{[2
]}

Sirin, Yakup ^{[1
]}

机构：

[1] Karadeniz Tech Univ, Dept Chem, TR-61080 Trabzon, Turkey

[2] Karadeniz Tech Univ, Dept Chem & Chem Proc Technol, TR-61080 Trabzon, Turkey

来源：

BIOORGANIC CHEMISTRY | 2019年 / 88卷

关键词：

Schiff base; beta-Lactam; Morpholine; Thiomorpholine; Azole; Antitubercular activity; Antiurease activity; Acethylcolinesterase; Antioxidant; BIOLOGICAL EVALUATION; ANTIBACTERIAL; PRODUCTS; DRUG;

D O I：

10.1016/j.bioorg.2019.102928

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this study, new Schiff bases and beta-lactam derivatives containing morpholine and thio morpholine nuclei were synthesized. Antimicrobial, antioxidant, antimicrobial and antioxidant properties of all synthesized compounds were investigated and highly effective products were obtained. In this context, new effective structures were introduced to the literature.

引用

页数：9

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