Studies of the interaction of Co(III) complex with DNA

被引:0
作者
Song, YM [1 ]
Kang, JW
Gao, JZ
Feng, YG
机构
[1] NW Normal Univ, Dept Chem, Lanzhou 730070, Peoples R China
[2] Lanzhou Teachers Coll, Dept Chem, Lanzhou 730070, Peoples R China
关键词
cobalt(III); calf thymus DNA; intercalative binding; electrostatic binding;
D O I
暂无
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
In order to understand how the size of the ligands' planarties can effect the complexes of binding to DNA, the binding of the complexes [Co(en)(3)](3+) ,[Co(bpy)(3)](3+) and [Co(phen)(3)](3+) to calf thymus DNA was investigated with spectroscopic and fluorometric methods. The three complexes bind to DNA by electrostatic fashion, for [Co(phen)(3)](3+) also exists intercalation mode. The intercalate binding affinities was consistent with the ligands's planarities.
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页码:53 / 57
页数:5
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