Studies of the interaction of Co(III) complex with DNA

被引：0

作者：

Song, YM ^{[1
]}

Kang, JW

Gao, JZ

Feng, YG

机构：

[1] NW Normal Univ, Dept Chem, Lanzhou 730070, Peoples R China

[2] Lanzhou Teachers Coll, Dept Chem, Lanzhou 730070, Peoples R China

来源：

CHINESE JOURNAL OF INORGANIC CHEMISTRY | 2000年 / 16卷 / 01期

关键词：

cobalt(III); calf thymus DNA; intercalative binding; electrostatic binding;

D O I：

暂无

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

In order to understand how the size of the ligands' planarties can effect the complexes of binding to DNA, the binding of the complexes [Co(en)(3)](3+) ,[Co(bpy)(3)](3+) and [Co(phen)(3)](3+) to calf thymus DNA was investigated with spectroscopic and fluorometric methods. The three complexes bind to DNA by electrostatic fashion, for [Co(phen)(3)](3+) also exists intercalation mode. The intercalate binding affinities was consistent with the ligands's planarities.

引用

页码：53 / 57

页数：5

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