Acupuncture and PC6 stimulation for the prevention of postoperative nausea and vomiting in patients undergoing elective laparoscopic resection of colorectal cancer: a study protocol for a three-arm randomised pilot trial

被引：22

作者：

Kim, Kun Hyung ^{[1
]}

Kim, Dae Hun ^{[2
]}

Bae, Ji Min ^{[2
]}

Son, Gyung Mo ^{[3
]}

Kim, Kyung Hee ^{[3
]}

Hong, Seung Pyo ^{[2
]}

Yang, Gi Young ^{[1
]}

Kim, Hee Young ^{[4
]}

机构：

[1] Pusan Natl Univ, Sch Korean Med, Yangsan, South Korea

[2] Pusan Natl Univ, Korean Med Hosp, Dept Acupuncture & Moxibust, Yangsan, South Korea

[3] Pusan Natl Univ, Dept Surg, Yangsan Hosp, Yangsan, South Korea

[4] Pusan Natl Univ, Dept Anesthesia & Pain Med, Yangsan Hosp, Yangsan, South Korea

来源：

BMJ OPEN | 2017年 / 7卷 / 01期

关键词：

acupuncture; postoperative nausea and vomiting; colorectal cancer; omplementary and alternative medicine; SERVICE QUALITY; SURGERY; SATISFACTION; RECOVERY; SURVIVAL; ONCOLOGY; QLQ-C30;

D O I：

10.1136/bmjopen-2016-013457

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction This study aims to assess the feasibility of acupuncture and a Pericardium 6 (PC6) wristband as an add-on intervention of antiemetic medication for the prevention of postoperative nausea and vomiting (PONV) in patients undergoing elective laparoscopic colorectal cancer resection. Methods and analysis A total of 60 participants who are scheduled to undergo elective laparoscopic resection of colorectal cancer will be recruited. An enhanced recovery after surgery protocol using standardised antiemetic medication will be provided for all participants. Participants will be equally randomised into acupuncture plus PC6 wristband (Acupuncture), PC6 wristband alone (Wristband), or no acupuncture or wristband (Control) groups using computer-generated random numbers concealed in opaque, sealed, sequentially numbered envelopes. For the acupuncture combined with PC6 wristband group, the embedded auricular acupuncture technique for preoperative anxiolysis and up to three sessions of acupuncture treatments with manual and electrical stimulation within 48hours after surgery will be provided by qualified Korean medicine doctors. The PC6 wristband will be applied in the Acupuncture and Wristband groups, beginning 1hour before surgery and lasting 48hours postoperatively. The primary outcome will be the number of participants who experience moderate or severe nausea, defined as nausea at least 4 out of 10 on a severity numeric rating scale or vomiting at 24hours after surgery. Secondary outcomes, including symptom severity, participant global assessments and satisfaction, quality of life, physiological recovery, use of medication and length of hospital stay, will be assessed. Adverse events and postoperative complications will be measured for 1month after surgery. Ethics and dissemination All participants will provide written informed consent. The study has been approved by the institutional review board (IRB). This pilot trial will inform a full-scale randomised trial of acupuncture combined with PC6 stimulation for the prevention of PONV in patients undergoing elective laparoscopic colorectal cancer surgery.

引用

页数：9

共 21 条

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