A MLC-based inversely optimized 3D spatially fractionated grid radiotherapy technique

被引：28

作者：

Jin, Jian-Yue ^{[1
]}

Zhao, Bo ^{[2
]}

Kaminski, Joseph M. ^{[1
]}

Wen, Ning ^{[2
]}

Huang, Yimei ^{[2
]}

Vender, John ^{[3
]}

Chetty, Indrin J. ^{[2
]}

Kong, Feng-Ming ^{[1
]}

机构：

[1] Georgia Regents Univ, Radiat Oncol, Augusta, GA 30912 USA

[2] Henry Ford Hosp, Radiat Oncol, Detroit, MI 48202 USA

[3] Georgia Regents Univ, Neurosurg, Augusta, GA 30912 USA

来源：

RADIOTHERAPY AND ONCOLOGY | 2015年 / 117卷 / 03期

关键词：

Grid therapy; Spatially fractionated radiotherapy; Ablative radiation; Immune-response; Film dosimetry; RADIATION; THERAPY; CANCER; BEAMS;

D O I：

10.1016/j.radonc.2015.07.047

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This study presents a MLC-based, 3D grid-therapy technique with characteristics of both 3D-conformal-radiotherapy and grid-therapy. It generates a brachytherapy-like dose distribution, with D50% of 20, 9.8, 5.4 and 2.9-Gy, for the spheres, target, 1 cm-outershell and 2 cm-outershell, respectively. It may provide a strategy to deliver ablative doses to large tumors safely. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

引用

页码：483 / 486

页数：4

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