The clinical presentation and management of carcinoid heart disease

被引：33
|
作者：
Dobson, R. [1 ,5 ]
Burgess, M. I. [1 ,2 ]
Pritchard, D. M. [3 ,4 ]
Cuthbertson, D. J. [1 ,5 ]
机构：
[1] Aintree Univ Hosp NHS Fdn Trust, Neuroendocrine Tumour Grp, Liverpool L9 7AL, Merseyside, England
[2] Aintree Univ Hosp NHS Fdn Trust, Dept Cardiol, Liverpool L9 7AL, Merseyside, England
[3] Univ Liverpool, Inst Translat Med, Dept Gastroenterol, Liverpool L69 3GE, Merseyside, England
[4] Royal Liverpool Univ Hosp, Neuroendocrine Tumour Grp, Liverpool L7 8XP, Merseyside, England
[5] Univ Liverpool, Inst Ageing & Chron Dis, Dept Obes & Endocrinol, Liverpool L69 3GA, Merseyside, England
来源：
INTERNATIONAL JOURNAL OF CARDIOLOGY | 2014年 / 173卷 / 01期
关键词：
Carcinoid heart disease; Valve surgery; Management; ENETS CONSENSUS GUIDELINES; BRAIN NATRIURETIC PEPTIDE; NEUROENDOCRINE-TUMORS; CARDIAC-SURGERY; VALVE-REPLACEMENT; HEPATIC RESECTION; GROWTH-FACTOR; ECHOCARDIOGRAPHY; DIAGNOSIS; OUTCOMES;
D O I：
10.1016/j.ijcard.2014.02.037
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Carcinoid heart disease is a major cause of morbidity and mortality in patients with metastatic neuroendocrine tumours (NETs). Although cases of carcinoid syndrome and severe carcinoid heart disease requiring urgent intervention are well described, many patients with significant carcinoid heart disease may have insidious symptoms or even be asymptomatic. As haemodynamically significant carcinoid heart disease may be clinically silent, specific and individualised considerations must be made as to the most appropriate clinical criteria and time point at which surgical valve replacement should be undertaken in patients with carcinoid heart disease. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：29 / 32
页数：4
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