Epidemiological factors associated with treated incidence of first-episode non-affective psychosis in Cantabria: insights from the Clinical Programme on Early Phases of Psychosis

被引:137
作者
Pelayo-Teran, Jose M. [1 ]
Perez-Iglesias, Rocio [1 ]
Ramirez-Bonilla, MariLuz [1 ]
Gonzalez-Blanch, Cesar [1 ]
Martinez-Garcia, Obdulia [1 ]
Pardo-Garcia, Gema [1 ]
Rodriguez-Sanchez, Jose M. [1 ]
Roiz-Santianez, Roberto [1 ]
Tordesillas-Gutierrez, Diana [1 ]
Mata, Ignacio [1 ]
Luis Vazquez-Barquero, Jose [1 ]
Crespo-Facorro, Benedicto [1 ]
机构
[1] Univ Cantabria, Dept Psychiat, Univ Hosp Marques de Valdecilla, Sch Med, E-39005 Santander, Spain
关键词
epidemiology; first-episode psychosis; risk factor; schizophrenia; sociodemographic;
D O I
10.1111/j.1751-7893.2008.00074.x
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Aim: The aim of the study was to analyse the treated incidence of schizophrenia in Cantabria (Northern Spain) and the sociodemographic risk factors associated with the illness onset. Methods: Data were obtained from patients included in the Cantabria's Clinical Programme on First-Episode Psychosis (schizophrenia spectrum DSM-IV diagnosis) from 2001 to 2005, from the Cantabria first-episode schizophrenia study (carried out between 1988 and 1989) and from the 2001 Spanish census. Results: Annual incidence was 1.38 per 10 000 inhabitants in the risk-ageperiod. Identified risk factors were male gender (relative risk (RR): 1.61), age 15-25 years (RR: 3.48), unemployment (RR: 2.82), single status (RR: 5.88), low educational level (RR: 4.38), urban environment (RR: 1.62) and cannabis consumption (odds ratio: 12.83). The incidence in females was significantly lower than the one obtained 15 years ago. Conclusions: The reported factors suggest that underlying biological and social factors modulate the risk of psychosis. This balance operates differently in males and females.
引用
收藏
页码:178 / 187
页数:10
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