Ellagic Acid and Its Role in Chronic Diseases

被引:107
作者
Derosa, Giuseppe [1 ,2 ,3 ,4 ]
Maffioli, Pamela [1 ,5 ]
Sahebkar, Amirhossein [6 ,7 ]
机构
[1] Univ Pavia, Dept Internal Med & Therapeut, Fdn IRCCS Policlin S Matteo, Ple C Golgi 2, I-27100 Pavia, Italy
[2] Fdn IRCCS Policlin San Matteo, Ctr Prevent Surveillance Diag & Treatment Rare Di, Pavia, Italy
[3] Univ Pavia, Ctr Study Endocrine Metab Pathophysiol & Clin Res, Pavia, Italy
[4] Univ Pavia, Mol Med Lab, Pavia, Italy
[5] Univ Pavia, PhD Sch Expt Med, Pavia, Italy
[6] Mashhad Univ Med Sci, Biotechnol Res Ctr, Mashhad, Iran
[7] Mashhad Univ Med Sci, Dept Med Biotechnol, Sch Med, POB 91779-48564, Mashhad, Iran
来源
ANTI-INFLAMMATORY NUTRACEUTICALS AND CHRONIC DISEASES | 2016年 / 928卷
关键词
Ellagic acid; Cancer; Chronic inflammation; Diabetes; POMEGRANATE JUICE; APOPTOSIS; GLYCATION; PATHWAY;
D O I
10.1007/978-3-319-41334-1_20
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Ellagic acid is a natural anti-oxidant phenol found in numerous fruits and vegetables, in particular pomegranate, persimmon, raspberry, black raspberry, strawberry, peach, plumes, nuts (walnuts, almonds), and wine. The anti-proliferative and anti-oxidant properties of ellagic acid have prompted research into its potential health benefits. The aim of this chapter will be to summarize potential benefits of ellagic acid supplementation in chronic diseases.
引用
收藏
页码:473 / 479
页数:7
相关论文
共 20 条
[1]   Hepatitis C virus inhibitory hydrolysable tannins from the fruits of Terminalia chebula [J].
Ajala, Olusegun S. ;
Jukov, Azzaya ;
Ma, Chao-Mei .
FITOTERAPIA, 2014, 99 :117-123
[2]   Dietary supplementation of an ellagic acid-enriched pomegranate extract attenuates chronic colonic inflammation in rats [J].
Angeles Rosillo, Maria ;
Sanchez-Hidalgo, Marina ;
Cardeno, Ana ;
Aparicio-Soto, Marina ;
Sanchez-Fidalgo, Susana ;
Villegas, Isabel ;
Alarcon-de-la-Lastra, Catalina .
PHARMACOLOGICAL RESEARCH, 2012, 66 (03) :235-242
[3]   Analytical methods for assay of ellagic acid and its solubility studies [J].
Bala, I ;
Bhardwaj, V ;
Hariharan, S ;
Kumar, MNVR .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2006, 40 (01) :206-210
[4]   Ellagic acid in Emblica officinalis exerts anti-diabetic activity through the action on β-cells of pancreas [J].
Fatima, Noor ;
Hafizur, Rahman M. ;
Hameed, Abdul ;
Ahmed, Shakil ;
Nisar, Maliha ;
Kabir, Nurul .
EUROPEAN JOURNAL OF NUTRITION, 2017, 56 (02) :591-601
[5]   Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing [J].
Gil, MI ;
Tomás-Barberán, FA ;
Hess-Pierce, B ;
Holcroft, DM ;
Kader, AA .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2000, 48 (10) :4581-4589
[6]   The dietary hydrolysable tannin punicalagin releases ellagic acid that induces apoptosis in human colon adenocarcinoma Caco-2 cells by using the mitochondrial pathway [J].
Larrosa, Mar ;
Tomas-Barberan, Francisco A. ;
Espin, Juan Carlos .
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2006, 17 (09) :611-625
[7]  
Liu WX, 2014, FOOD FUNCT, V5, P2996, DOI [10.1039/C4FO00538D, 10.1039/c4fo00538d]
[8]   Intestinal anti-inflammatory activity of ellagic acid in the acute and chronic dextrane sulfate sodium models of mice colitis [J].
Marin, Marta ;
Maria Giner, Rosa ;
Rios, Jose-Luis ;
Carmen Recio, Maria .
JOURNAL OF ETHNOPHARMACOLOGY, 2013, 150 (03) :925-934
[9]   Virtual screening of natural inhibitors to the predicted HBx protein structure of Hepatitis B Virus using molecular docking for identification of potential lead molecules for liver cancer [J].
Pathak, Rajesh Kumar ;
Baunthiyal, Mamta ;
Taj, Gohar ;
Kumar, Anil .
BIOINFORMATION, 2014, 10 (07) :428-435
[10]   Small molecule inhibitors of HCV replication from Pomegranate [J].
Reddy, B. Uma ;
Mullick, Ranajoy ;
Kumar, Anuj ;
Sudha, Govindarajan ;
Srinivasan, Narayanaswamy ;
Das, Saumitra .
SCIENTIFIC REPORTS, 2014, 4