Antioxidant enzyme determination and a study of lipid peroxidation in renal transplantation

被引:24
|
作者
Fernandez, RP [1 ]
Mateo, MCM [1 ]
De Vega, L [1 ]
Bustamante, JB [1 ]
Herrero, M [1 ]
Munguira, EB [1 ]
机构
[1] Univ Valladolid, Sch Sci, Dept Biochem, E-47005 Valladolid, Spain
关键词
catalase; superoxide dismutase (SOD); malondialdehyde (MDA); renal transplantation;
D O I
10.1081/JDI-120005369
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The aim of this study was to evaluate the antioxidant enzymes, catalase (CAT) and superoxide dismutase (SOD), in renal transplant patients and at the same time to report on the degree of lipid peroxidation observed in these patients. In order to do so we measured erythrocyte malondialdehyde (MDA), a product of lipid peroxidation. These measurements were made at different times: before the transplant, 48 h after the transplant, a week after the transplant and two weeks after the transplant. The values reported were compared with a control group. The results showed that there was a higher MDA level in the transplant group than in the control group one week after the transplant. In addition, two weeks after the transplant, the activities of CAT and SOD were higher in the transplant group than in the control group.
引用
收藏
页码:353 / 359
页数:7
相关论文
共 50 条
  • [11] Lipid peroxidation and antioxidant enzymes in children with chronic renal failure
    Zwolinska, D
    Grzeszczak, W
    Kilis-Pstrusinska, K
    Szprynger, K
    Szczepanska, M
    PEDIATRIC NEPHROLOGY, 2004, 19 (08) : 888 - 892
  • [12] Lipid peroxidation and antioxidant enzymes in children with chronic renal failure
    Danuta Zwolińska
    Władysław Grzeszczak
    Katarzyna Kiliś-Pstrusińska
    Krystyna Szprynger
    Maria Szczepańska
    Pediatric Nephrology, 2004, 19 : 888 - 892
  • [13] ROS generation, lipid peroxidation and antioxidant enzyme activities in the aging brain
    Leutner, S
    Eckert, A
    Müller, WE
    JOURNAL OF NEURAL TRANSMISSION, 2001, 108 (8-9) : 955 - 967
  • [14] Antioxidant enzyme activities, metallothioneins and lipid peroxidation as biomarkers in Ruditapes decussatus?
    Geret, F
    Serafim, A
    Bebianno, MJ
    ECOTOXICOLOGY, 2003, 12 (05) : 417 - 426
  • [15] ROS generation, lipid peroxidation and antioxidant enzyme activities in the aging brain
    S. Leutner
    A. Eckert
    W. E. Müller
    Journal of Neural Transmission, 2001, 108 : 955 - 967
  • [16] Lipid peroxidation and antioxidant enzyme activities of Euphorbia milii hyperhydric shoots
    Dewir, Y. H.
    Chakrabarty, D.
    Ali, M. B.
    Hahn, E. J.
    Paek, K. Y.
    ENVIRONMENTAL AND EXPERIMENTAL BOTANY, 2006, 58 (1-3) : 93 - 99
  • [17] Antioxidant Enzyme Activities, Metallothioneins and Lipid Peroxidation as Biomarkers in Ruditapes decussatus?
    Florence Geret
    Angela Serafim
    Maria João Bebianno
    Ecotoxicology, 2003, 12 : 417 - 426
  • [18] Lipid Peroxidation and Antioxidant Enzyme Activity in Response to Interval Hypoxic Training
    S. A. El'chaninova
    I. V. Smagina
    N. A. Korenyak
    B. Ya. Varshavskii
    Human Physiology, 2003, 29 (3) : 324 - 327
  • [19] Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar disorder
    Kuloglu, M
    Ustundag, B
    Atmaca, M
    Canatan, H
    Tezcan, AE
    Cinkilinc, N
    CELL BIOCHEMISTRY AND FUNCTION, 2002, 20 (02) : 171 - 175
  • [20] Water stress, antioxidant enzyme activity and lipid peroxidation in wheat seedling
    Esfandiari, Ezzat-Ollah
    Shakiba, Mohammad Reza
    Mahboob, Soltan Ali
    Alyari, Hoshang
    Toorchi, Mahmood
    JOURNAL OF FOOD AGRICULTURE & ENVIRONMENT, 2007, 5 (01): : 149 - 153