APOE -: 491 promoter polymorphism is a risk factor for late-onset Alzheimer's disease

被引：33

作者：

Casadei, VM

Ferri, C

Veglia, F

Gavazzi, A

Salani, G

Cattaneo, M

Sorbi, S

Annoni, G

Licastro, F

Mariani, C

Franceschi, M

Grimaldi, LME

机构：

[1] Ist Sci San Raffaele, Clin Santa Maria Castellanza, Neuroimmunol Unit, Dept Neurosci, I-20132 Milan, Italy

[2] Ist Sci San Raffaele, Clin Santa Maria Castellanza, Neuroimmunol Unit, Biostat Unit, I-20132 Milan, Italy

[3] Ist Sci San Raffaele, Clin Santa Maria Castellanza, Dept Neurol, I-20132 Milan, Italy

[4] CNR, Ist Tecnol Biomed Avanzate, I-20131 Milan, Italy

[5] Univ Florence, Dept Neurol & Psychiat Sci, I-50121 Florence, Italy

[6] Univ Milan, Dept Geriatr, I-20122 Milan, Italy

[7] Univ Bologna, Dept Expt Pathol, I-40126 Bologna, Italy

[8] IRCCS Santa Maria Nascente, Neurorehabil Unit, Milan, Italy

[9] IRCCS Oasi Maria Santissima, Troina, Italy

来源：

NEUROLOGY | 1999年 / 53卷 / 08期

关键词：

APOE; AD; polymorphisms;

D O I：

10.1212/WNL.53.8.1888

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：1888 / 1889

页数：2

共 7 条

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[5] APOE genotype predicts when -: not whether -: one is predisposed to develop Alzheimer disease
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[6] Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE
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[7] The -491A/T apolipoprotein E promoter polymorphism association with Alzheimer's disease: independent risk and linkage disequilibrium with the known APOE polymorphism
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[J]. NEUROSCIENCE LETTERS, 1998, 252 (02) : 95 - 98

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