Optimization of cultivation medium for the production of Bacillus intermedius 3-19 glutamyl endopeptidase

被引：0
|
作者：
Gabdrakhmanova, LA
Balaban, NP
Sharipova, MR
Tokmakova, YS
Sokolova, EA
Rudenskaya, GN
Leshchinskaya, IB
机构：
[1] Kazan VI Lenin State Univ, Kazan 420008, Russia
[2] Moscow MV Lomonosov State Univ, Moscow 119899, Russia
来源：
MICROBIOLOGY | 2002年 / 71卷 / 03期
基金：
俄罗斯基础研究基金会;
关键词：
glutamyl endopeptidase; spore-forming bacteria; amino acids; biosynthesis; factorial experimental design;
D O I：
10.1023/A:1015894325665
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The effect of some components of cultivation medium on the growth of the streptomycin-resistant Bacillus intermedius strain 3-19 and on the production of glutamyl endopeptidase was investigated using factorial experimental design, which allowed the concentrations of peptone and inorganic phosphate to be optimized for the maximum production of the enzyme. Experiments with different peptones and casamino acids showed that the enzyme production is maximum with peptone 3 of plant origin. The addition of casamino acids or amino acids to the peptone-containing cultivation medium inhibited the production of glutamyl endopeptidase.
引用
收藏
页码：275 / 280
页数：6
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