Functional and survival outcomes in elderly patients undergoing transoral robotic surgery

被引:7
|
作者
Philips, Ramez [1 ]
Topf, Michael C. [2 ]
Crawley, Meghan B. [3 ]
Swendseid, Brian [1 ]
Luginbuhl, Adam [1 ]
Curry, Joseph [1 ]
Cognetti, David [1 ]
机构
[1] Thomas Jefferson Univ Hosp, Dept Otolaryngol Head & Neck Surg, 6th Floor,925 Chestnut St, Philadelphia, PA 19107 USA
[2] Vanderbilt Univ, Med Ctr, Dept Otolaryngol Head & Neck Surg, 1215 21st Ave S Suite 7209, Nashville, TN 37232 USA
[3] Cleveland Clin, Head & Neck Inst, 9500 Euclid Ave A71, Cleveland, OH 44106 USA
关键词
Transoral robotic surgery; Head and neck cancer; Elderly; Age; Survival; Functional status; Enteric feed dependence; Squamous cell carcinoma; Human papillomavirus; Non-elderly; SQUAMOUS-CELL CARCINOMA; QUALITY-OF-LIFE; OROPHARYNGEAL CANCER; HUMAN-PAPILLOMAVIRUS; RADIATION-THERAPY; HEAD; INTENSITY; DYSPHAGIA;
D O I
10.1016/j.oraloncology.2020.104954
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Objectives: To determine if elderly patients (>= 70 years) have differences in functional and survival outcomes compared to non-elderly patients (< 70 years) following transoral robotic surgery. Materials and methods: A retrospective cohort study was conducted on patients undergoing robotic surgery for head and neck cancer at a tertiary institution from 2011 to 2016. Functional status was evaluated with diet, enteric feeding status, Functional Oral Intake Scale (FOIS), tracheostomy tube placement, and unplanned readmission. Kaplan Meier method and Cox proportional hazard model were used to assess overall survival (OS) and disease-free survival (DFS) between elderly and non-elderly patients. Results: Two hundred and forty-six patients met inclusion criteria. The mean age of the cohort was 63.5 +/- 9.74 years. There were 64 patients (26.0%) that were >= 70 years. Elderly patients were more likely to be discharged with enteric access (p < 0.002). As early as 3 months, there was no significant difference in need for enteric feeds, diet, or FOIS score. There was no difference in tracheostomy tube rates and unplanned readmission between both cohorts. There was no significant difference in OS and DFS between age groups when stratified by p16 status. Conclusions: Elderly patients are more likely to require perioperative enteric feeding, but 3-month, 1-year, and 2 year functional outcomes are comparable to younger patients. Survival outcomes are similar in both populations.
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页数:9
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