Low concentrations of propyzamide and oryzalin alter microtubule dynamics in Arabidopsis epidermal cells

被引：114

作者：

Nakamura, M ^{[1
]}

Naoi, K ^{[1
]}

Shoji, T ^{[1
]}

Hashimoto, T ^{[1
]}

机构：

[1] Nara Inst Sci & Technol, Grad Sch Biol Sci, Ikoma, Nara 6300192, Japan

来源：

PLANT AND CELL PHYSIOLOGY | 2004年 / 45卷 / 09期

关键词：

Arabidopsis; dynamic instability; microtubules; oryzalin; propyzamide;

D O I：

10.1093/pcp/pch300

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Previous studies showed that sub-micromolar concentrations of the microtubule-targeting herbicide propyzamide cause a right-handed helical arrangement of cortical microtubule arrays and left-handed twisting in elongating Arabidopsis epidermal cells. When seedlings were grown in the presence of 1-2 muM propyzamide or 50-100 nM oryzalin, we show that microtubules spent more time in a paused state in which they exhibited little net change in length. The drug treatment also resulted in slower growth and shortening velocities, increased catastrophe, and an overall decrease in microtubule turnover. A reduction in microtubule dynamic turnover may underlie the drug-induced rearrangement of cortical arrays.

引用

页码：1330 / 1334

页数：5

共 24 条

[1] Herbicide resistance caused by spontaneous mutation of the cytoskeletal protein tubulin [J].