ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

被引：4681
作者：
Bindea, Gabriela [1 ,2 ,3 ,5 ]
Mlecnik, Bernhard [1 ,2 ,3 ]
Hackl, Hubert [5 ]
Charoentong, Pornpimol [5 ]
Tosolini, Marie [1 ,2 ,3 ]
Kirilovsky, Amos [1 ,2 ,3 ]
Fridman, Wolf-Herman [1 ,2 ,3 ,4 ]
Pages, Franck [1 ,2 ,3 ,4 ]
Trajanoski, Zlatko [5 ]
Galon, Jerome [1 ,2 ,3 ,4 ]
机构：
[1] INSERM, U872, AVENIR Team, F-75006 Paris, France
[2] Univ Paris 05, Paris, France
[3] Univ Paris 06, Paris, France
[4] HEGP, AP HP, Paris, France
[5] Graz Univ Technol, Inst Genom & Bioinformat, A-8010 Graz, Austria
来源：
BIOINFORMATICS | 2009年 / 25卷 / 08期
关键词：
PROTEOMIC DATA; INFORMATION; SOFTWARE; TOOL;
D O I：
10.1093/bioinformatics/btp101
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term network. It can analyze one or compare two lists of genes and comprehensively visualizes functionally grouped terms. A one-click update option allows ClueGO to automatically download the most recent GO/KEGG release at any time. ClueGO provides an intuitive representation of the analysis results and can be optionally used in conjunction with the GOlorize plug-in.
引用
收藏
页码：1091 / 1093
页数：3
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