ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

被引：4798

作者：

Bindea, Gabriela ^{[1
,2
,3
,5
]}

Mlecnik, Bernhard ^{[1
,2
,3
]}

Hackl, Hubert ^{[5
]}

Charoentong, Pornpimol ^{[5
]}

Tosolini, Marie ^{[1
,2
,3
]}

Kirilovsky, Amos ^{[1
,2
,3
]}

Fridman, Wolf-Herman ^{[1
,2
,3
,4
]}

Pages, Franck ^{[1
,2
,3
,4
]}

Trajanoski, Zlatko ^{[5
]}

Galon, Jerome ^{[1
,2
,3
,4
]}

机构：

[1] INSERM, U872, AVENIR Team, F-75006 Paris, France

[2] Univ Paris 05, Paris, France

[3] Univ Paris 06, Paris, France

[4] HEGP, AP HP, Paris, France

[5] Graz Univ Technol, Inst Genom & Bioinformat, A-8010 Graz, Austria

来源：

BIOINFORMATICS | 2009年 / 25卷 / 08期

关键词：

PROTEOMIC DATA; INFORMATION; SOFTWARE; TOOL;

D O I：

10.1093/bioinformatics/btp101

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term network. It can analyze one or compare two lists of genes and comprehensively visualizes functionally grouped terms. A one-click update option allows ClueGO to automatically download the most recent GO/KEGG release at any time. ClueGO provides an intuitive representation of the analysis results and can be optionally used in conjunction with the GOlorize plug-in.

引用

页码：1091 / 1093

页数：3

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