Uses of Nanoparticles for Central Nervous System Imaging and Therapy

被引:58
作者
Provenzale, J. M. [1 ,2 ,3 ]
Silva, G. A. [4 ,5 ]
机构
[1] Duke Univ, Med Ctr, Neuroradiol Div, Dept Radiol, Durham, NC 27710 USA
[2] Emory Univ, Sch Med, Dept Radiol, Atlanta, GA 30322 USA
[3] Emory Univ, Sch Med, Dept Oncol & Biomed Engn, Atlanta, GA 30322 USA
[4] Univ Calif San Diego, Dept Bioengn, San Diego, CA 92103 USA
[5] Univ Calif San Diego, Dept Ophthalmol, San Diego, CA 92103 USA
关键词
IRON-OXIDE NANOPARTICLES; DRUG-DELIVERY SYSTEMS; MAGNETIC-RESONANCE; IN-VIVO; SPINAL-CORD; STEM-CELLS; BRAIN; NANOTECHNOLOGY; DOXORUBICIN; MR;
D O I
10.3174/ajnr.A1590
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Applications of nanotechnology to medicine are leading to novel means of imaging living systems and of delivering therapy. Much nanotechnology research is focused on methods for imaging central nervous system functions and disease states. In this review, the principles of nanoparticle design and function are discussed with specific emphasis on applications to neuroradiology. In addition to innovative forms of imaging, this review describes therapeutic uses of nanoparticles, such as drug delivery systems, neuroprotection devices, and methods for tissue regeneration.
引用
收藏
页码:1293 / 1301
页数:9
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