Anodic modification of proline derivatives using a lithium perchlorate/nitromethane electrolyte

被引：44

作者：

Kim, S ^{[1
]}

Hayashi, K ^{[1
]}

Kitano, Y ^{[1
]}

Tada, M ^{[1
]}

Chiba, K ^{[1
]}

机构：

[1] Tokyo Univ Agr & Technol, Bioorgan Chem Lab, Fuchu, Tokyo 1838509, Japan

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 21期

关键词：

D O I：

10.1021/ol026713z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHIC] N-Acyliminium cation of prolines was efficiently generated to accumulate in an undivided cell at 0 degreesC by an anodic oxidation of N-acylprolines or alpha'-phenylsulfanylated N-acylproline derivatives in a lithium perchlorate/nitromethane solution. The iminium cation intermediates gave modified prollnes by a reaction with nucleophiles under mild conditions.

引用

页码：3735 / 3737

页数：3

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