Utilization of the intestinal tract as a delivery system for urogenital Probiotics

被引:84
作者
Morelli, L
Zonenenschain, D
Del Piano, M
Cognein, P
机构
[1] UCSC, Fac Agraria, Ist Microbiol, I-29100 Piacenza, Italy
[2] Azienda Osped Santa Maria Maggiore, Novara, Italy
关键词
vagina; probiotic; lactobacillus;
D O I
10.1097/01.mcg.0000128938.32835.98
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Orally consumed viable bacteria with proposed beneficial health effects, the so-called probiotics, are increasingly used to treat disorders of the gastrointestinal tract. It has been recently suggested that specifically selected lactobacilli could have a therapeutic role in female urogenital tract infections. It has been also suggested that some of these bacteria could be not intravaginally instilled, but also orally delivered. The authors investigate the ability of lactobacilli isolated from the vagina to survive gastrointestinal tract transit, and establish a link between the rate of intestinal survival and vaginal colonization.
引用
收藏
页码:S107 / S110
页数:4
相关论文
共 12 条
[1]  
[Anonymous], 2002, GUIDELINES EVALUATIO
[2]   Characterization of the aggregation promoting factor from Lactobacillus gasseri, a vaginal isolate [J].
Boris, S ;
Suarez, JE ;
Barbes, C .
JOURNAL OF APPLIED MICROBIOLOGY, 1997, 83 (04) :413-420
[3]  
Food and Agriculture Organization of the United Nations [FAO] and World Health Organization [WHO], 2001, Evaluation of health and nutritional properties of powder milk and live lactic acid bacteria. Report from FAO/WHO expert consultation
[4]   Persistence of Lactobacillus fermentum RC-14 and Lactobacillus rhamnosus GR-1 but not L-rhamnosus GG in the human vagina as demonstrated by randomly amplified polymorphic DNA [J].
Gardiner, GE ;
Heinemann, C ;
Bruce, AW ;
Beuerman, D ;
Reid, G .
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 2002, 9 (01) :92-96
[5]  
GIORGI A, 1987, MICROBIOLOGICA, V10, P377
[6]   Characterisation of ropy slime-producing Lactobacillus sakei using repetitive element sequence-based PCR [J].
Hyytiä-Trees, E ;
Lyhs, U ;
Korkeala, H ;
Björkroth, J .
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 1999, 50 (03) :215-219
[7]  
Morelli L, 2000, Curr Issues Intest Microbiol, V1, P59
[8]   Oral use of Lactobacillus rhamnosus GR-1 and L-fermentum RC-14 significantly alters vaginal flora:: randomized, placebo-controlled trial in 64 healthy women [J].
Reid, G ;
Charbonneau, D ;
Erb, J ;
Kochanowski, B ;
Beuerman, D ;
Poehner, R ;
Bruce, AW .
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 2003, 35 (02) :131-134
[9]   Probiotic Lactobacillus dose required to restore and maintain a normal vaginal flora [J].
Reid, G ;
Beuerman, D ;
Heinemann, C ;
Bruce, AW .
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 2001, 32 (01) :37-41
[10]   Oral probiotics can resolve urogenital infectious [J].
Reid, G ;
Bruce, AW ;
Frase, N ;
Heinemann, C ;
Owen, J ;
Henning, B .
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 2001, 30 (01) :49-52