Cystic fibrosis-related diabetes: a distinct condition

被引：3

作者：

Cano Megias, Marta ^{[1
]}

Gonzalez Albarran, Olga ^{[2
]}

机构：

[1] Hosp Univ Principe de Asturias, Serv Nefrol, Madrid, Spain

[2] Hosp Univ Ramon & Cajal, Serv Endocrinol & Nutr, Madrid, Spain

来源：

ENDOCRINOLOGIA Y NUTRICION | 2015年 / 62卷 / 01期

关键词：

Cystic fibrosis; Cystic fibrosis-related diabetes; Pulmonary function; GLUCOSE-TOLERANCE; MICROVASCULAR COMPLICATIONS; PULMONARY-FUNCTION; CLINICAL STATUS; YOUNG-CHILDREN; LONG-TERM; MORTALITY; MELLITUS; LUNG; PREDICTORS;

D O I：

10.1016/j.endonu.2014.06.010

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cystic fibrosis is the most common fatal inherited autosomal recessive disease in Caucasians, affecting approximately one out of every 2,000 births. Survival of patients with cystic fibrosis has significantly improved due to advances in respiratory and nutritional care, and their current average life expectancy is 30-40 years. Development of cystic fibrosis-related diabetes is a comorbidity that increases with age and may reach a prevalence up to 50% in adults. Its development is associated to impaired lung function and nutritional status, and early diagnosis and treatment are therefore essential to improve quality of life and performance status. Insulin therapy for diabetes and other early carbohydrate metabolism disorders may improve lung function and nutritional status of patients with cystic fibrosis. (C) 2014 SEEN. Published by Elsevier Espana, S.L.U. All rights reserved.

引用

页码：38 / 44

页数：7

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