Degradable biomaterials based on magnesium corrosion

被引：1448
作者：
Witte, Frank [1 ,2 ]
Hort, Norbert [3 ]
Vogt, Carla [4 ]
Cohen, Smadar [2 ]
Kainer, Karl Ulrich [3 ]
Willumeit, Regine [3 ]
Feyerabend, Frank [3 ]
机构：
[1] Hannover Med Sch, Lab Biomech & Biomat, D-30625 Hannover, Germany
[2] Ben Gurion Univ Negev, Dept Biotechnol Engn, IL-84105 Beer Sheva, Israel
[3] GKSS Forschungszentrum Geesthacht GmbH, Inst Mat Res, D-21502 Geesthacht, Germany
[4] Leibniz Univ Hannover, Inst Inorgan Chem, D-30167 Hannover, Germany
来源：
CURRENT OPINION IN SOLID STATE & MATERIALS SCIENCE | 2008年 / 12卷 / 5-6期
关键词：
Magnesium alloy; Biodegradable; Corrosion; In vivo; In vitro; Animal model; Implant;
D O I：
10.1016/j.cossms.2009.04.001
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Biodegradable metals are breaking the current paradigm in biomaterial science to develop only corrosion resistant metals. In particular, metals which consist of trace elements existing in the human body are promising candidates for temporary implant materials. These implants would be temporarily needed to provide mechanical support during the healing process of the injured or pathological tissue. Magnesium and its alloys have been investigated recently by many authors as a suitable biodegradable biomaterial. In this investigative review we would like to summarize the latest achievements and comment on the selection and use, test methods and the approaches to develop and produce magnesium alloys that are intended to perform clinically with an appropriate host response. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：63 / 72
页数：10
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