Acetylated, methylated, remodeled: chromatin states for gene regulation

被引:45
作者
Lusser, A [1 ]
机构
[1] Univ Innsbruck, Dept Biol Mol, A-6020 Innsbruck, Austria
关键词
D O I
10.1016/S1369-5266(02)00287-X
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The activity state of a gene is determined not only by sequence-specific regulatory factors but also by a complex network of co-acting proteins. Many of these proteins directly or indirectly affect the structure of the chromatin environment into which the gene is embedded. Recent studies of histone and DNA modifications support and refine the concept of the chromatin environment being key to the establishment and maintenance of transcriptional activity or repression.
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收藏
页码:437 / 443
页数:7
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