Carbapenemase genes and genetic platforms in Gram-negative bacilli: Enterobacteriaceae, Pseudomonas and Acinetobacter species

被引:162
作者
Diene, S. M. [1 ]
Rolain, J. -M. [1 ]
机构
[1] Aix Marseille Univ, CNRS 7278, URMITE, UM63,IRD 198,INSERM 1095, F-13385 Marseille 05, France
关键词
Acinetobacter; carbapenemases; Enterobacteriaceae; multidrug-resistant bacteria; Pseudomonas; METALLO-BETA-LACTAMASE; KLEBSIELLA-PNEUMONIAE; ANTIBIOTIC-RESISTANCE; MOLECULAR CHARACTERIZATION; CLINICAL ISOLATE; ESCHERICHIA-COLI; EMERGENCE; AERUGINOSA; BAUMANNII; IMIPENEM;
D O I
10.1111/1469-0691.12655
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The emergence and rapid spread of carbapenemases in Enterobacteriaceae, Pseudomonas and Acinetobacter (EPA) species is becoming a major public health crisis worldwide, and is responsible for large number of hospital-acquired and nosocomial infections. In this article, we review the current knowledge on the classification, phylogeny and genetic platforms of the main carbapenemases already described in Gram-negative bacteria.
引用
收藏
页码:831 / 838
页数:8
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