Enantioselective syntheses of (+)- and (-)-brazilin

被引：14

作者：

Javed, Umair ^{[1
]}

Karim, Moinul ^{[1
]}

Jahng, Katherine C. ^{[2
]}

Park, Jae-Gyu ^{[3
]}

Jahng, Yurngdong ^{[1
]}

机构：

[1] Yeungnam Univ, Coll Pharm, Kyongsan 712749, South Korea

[2] Univ Iowa, Dept Biochem, Iowa City, IA 52242 USA

[3] Pohang Technopk, Pohang 790834, South Korea

来源：

TETRAHEDRON-ASYMMETRY | 2014年 / 25卷 / 18-19期

关键词：

H-AE-MATOXYLIN; ANTIBACTERIAL PRINCIPLE; BRAZILIN; (+/-)-BRAZILIN; CONSTITUTION; DERIVATIVES; WOOD;

D O I：

10.1016/j.tetasy.2014.08.009

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Two enantiomers of brazilin were prepared in 9 steps from 7-hydroxychroman-4-one using the AD-mix-alpha and AD-mix-beta-directed enantioselective dihydroxylation of 3-(4-hydroxy-3-methoxy-phenyl)-2H-chromen-7-ol as a key step. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：1270 / 1274

页数：5

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