The Metabolism and Potential Bioactivity of Chlorophyll and Metallo-chlorophyll Derivatives in the Gastrointestinal Tract

被引：35

作者：

Zhong, Siqiong ^{[1
]}

Bird, Amanda ^{[1
,2
]}

Kopec, Rachel E. ^{[1
,3
]}

机构：

[1] Ohio State Univ, Dept Human Sci, OSU Interdisciplinary Nutr Grad Program, Columbus, OH 43214 USA

[2] Ohio State Univ, Dept Mol Genet, Columbus, OH 43214 USA

[3] Ohio State Univ, Foods Hlth Discovery Theme, Columbus, OH 43214 USA

来源：

MOLECULAR NUTRITION & FOOD RESEARCH | 2021年 / 65卷 / 07期

基金：

美国食品与农业研究所;

关键词：

dioxins; heterocyclic aromatic amines; metabolism; polyaromatic hydrocarbons; sodium copper chlorophyllin; sodium iron chlorophyllin; zinc chlorophyllin;

D O I：

10.1002/mnfr.202000761

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Chlorophyll is the vivid chromophore which imparts the green color to plant leaves, and is consumed by humans through green vegetables. The basic porphyrin structure of chlorophyll binds magnesium in plants, but can bind different divalent metals (e.g., copper, zinc, iron) facilitated by food processing techniques and/or chemical synthesis. This review covers the known elements of chlorophyll and metallo-chlorophyll absorption, distribution, metabolism, excretion in vitro and in vivo. The review discusses what is understood about the ability of these novel metallo-chlorophyll derivatives to deliver essential metals. This review also detail chlorophyll and metallo-chlorophyll toxin binding properties which largely occur during digestion, focusing on toxins including dioxins, heterocyclic aromatic amines, polyaromatic hydrocarbons, and aflatoxin. Finally, the article highlights the gaps in the understanding of the metabolism and metal and toxin-binding bioactivity of this family of molecules.

引用

页数：11

共 116 条

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