HPLC analysis of methylxanthines and selected drugs in urine samples

被引:0
作者
Baranowska, Irena
Plonka, Joanna
Baranowski, Jacek
机构
[1] Silesian Tech Univ, Dept Gen & Analyt Chem, PL-44100 Gliwice, Poland
[2] Univ Hosp, Dept Clin Physiol, SE-58185 Linkoping, Sweden
来源
CHEMIA ANALITYCZNA | 2006年 / 51卷 / 05期
关键词
methylxanthines; drugs; HPLC; urine;
D O I
暂无
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A HPLC system for seperation and determination of methylxanthines and selected drugs has been developed. Teophylline, 1-methylxanthine, 3-methylxanthine, 1,3-dimethyluric acid, caffeine, paracetemol, furosemide, dexamethasone, prednisolone, cafazolin and imipenem have been determined. A RP-18e column with a RP-18 pre-column and a DAD detector were used. Gradient elution with 0.05% TFA aqueous solution with acetononitrile at the flow rate of 0.8 mL min(-1) was applied. The developed system was used to determine the examined compounds in urine samples.
引用
收藏
页码:751 / 760
页数:10
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