Regulating actin-filament dynamics in vivo

被引：219
作者：
Chen, H [1 ]
Bernstein, BW
Bamburg, JR
机构：
[1] Colorado State Univ, Dept Biochem & Mol Biol, Ft Collins, CO 80523 USA
[2] Colorado State Univ, Mol Cellular & Integrat Neurosci Program, Ft Collins, CO 80523 USA
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 2000年 / 25卷 / 01期
关键词：
D O I：
10.1016/S0968-0004(99)01511-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The assembly and disassembly (i.e. turnover) of actin filaments in response to extracellular signals underlie a wide variety of basic cellular processes such as cell division, endocytosis and motility. The bulk turnover of subunits is 100-200 times faster in cells than with pure actin, suggesting a complex regulation in vivo. Significant progress has been made recently in identifying and clarifying the roles of several cellular proteins that coordinately regulate actin-filament turnover.
引用
收藏
页码：19 / 23
页数：5
相关论文
共 53 条
123456