Shape Control of Soft Nanoparticles and Their Assemblies

被引：83

作者：

Chen, Chao ^{[1
]}

Wylie, Ross A. L. ^{[1
]}

Klinger, Daniel ^{[2
]}

Connal, Luke A. ^{[1
]}

机构：

[1] Univ Melbourne, Dept Chem & Biomol Engn, Parkville, Vic 3010, Australia

[2] Free Univ Berlin, Dept Biol Chem & Pharm, Inst Pharm, Konigin Luise Str 2-4, D-14195 Berlin, Germany

来源：

CHEMISTRY OF MATERIALS | 2017年 / 29卷 / 05期

关键词：

BLOCK-COPOLYMER NANOPARTICLES; AQUEOUS DISPERSION POLYMERIZATION; PEPTIDE-AMPHIPHILE NANOFIBERS; PROTEIN-PROTEIN INTERFACES; ACID) DIBLOCK COPOLYMERS; DNA-ORIGAMI; CYLINDRICAL MICELLES; DRUG-DELIVERY; CONTROLLED LENGTH; NANOSCALE SHAPES;

D O I：

10.1021/acs.chemmater.6b04700

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Soft nanoparticles with precisely controlled shape and morphologies hold great potential for the preparation of novel materials with tailored chemical and biophysical properties. In this review, we highlight the synthetic approaches and hierarchical strategies to manipulate the shape and morphology of nanostructures assembled from four major building units, namely block copolymers, peptide amphiphiles, proteins and nucleic acid building blocks. Special attention is given to anisotropic, stimuli-responsive nano particles that are tuned by assembly conditions. Their tunable nature is of particular significance as it allows the design of smart and dynamic materials. The immediate and potential applications of these shape controlled nanostructures are also summarized together with their limitations.

引用

页码：1918 / 1945

页数：28

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