Stochastic transfer function for structured illumination microscopy

被引：13

作者：

Somekh, Michael G. ^{[1
]}

Hsu, Ken ^{[1
]}

Pitter, Mark C. ^{[1
]}

机构：

[1] Univ Nottingham, Inst Biophys Imaging & Opt Sci, Nottingham NG7 2RD, England

来源：

JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION | 2009年 / 26卷 / 07期

关键词：

RESOLUTION LIMIT; SUPERRESOLUTION;

D O I：

10.1364/JOSAA.26.001630

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

The stochastic transfer function extends the concept of the conventional transfer function by incorporating noise statistics, thus giving a measure of the signal-to-noise ratio at each spatial frequency. This provides a convenient and standardized metric to assess the trade-off in terms of spatial frequency bandwidth and signal-to-noise ratio for a diverse range of resolution enhancement techniques. We apply this concept to structured illumination microscopy and compare its noise performance as a function of frequency with the conventional wide-field fluorescent microscope. The result suggests how a hybrid algorithm further improves the photon efficiency of the structured illumination technique. (C) 2009 Optical Society of America

引用

页码：1630 / 1637

页数：8

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