Treatment of Osteonecrosis in Systemic Lupus Erythematosus: A Review

被引：15

作者：

Ehmke, T. Andrew ^{[1
]}

Cherian, Jeffrey J. ^{[1
]}

Wu, Eddie S. ^{[1
]}

Jauregui, Julio J. ^{[1
]}

Banerjee, Samik ^{[1
]}

Mont, Michael A. ^{[1
]}

机构：

[1] Sinai Hosp, Ctr Joint Preservat & Replacement, Rubin Inst Adv Orthoped, Baltimore, MD 21215 USA

来源：

CURRENT RHEUMATOLOGY REPORTS | 2014年 / 16卷 / 09期

基金：

美国国家卫生研究院;

关键词：

Osteonecrosis; Hip; Knee; Shoulder; Joint replacement; Joint preservation; FEMORAL-HEAD OSTEONECROSIS; PULSED ELECTROMAGNETIC-FIELDS; ANTERIOR ROTATIONAL OSTEOTOMY; STEROID-INDUCED OSTEONECROSIS; TOTAL HIP-ARTHROPLASTY; EXTRACORPOREAL SHOCK-WAVES; 5-YEAR FOLLOW-UP; AVASCULAR NECROSIS; CORE DECOMPRESSION; ATRAUMATIC OSTEONECROSIS;

D O I：

10.1007/s11926-014-0441-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Osteonecrosis (ON) is a devastating illness that can lead to severe joint disease in young patients. The pathogenesis of ON is largely unknown; however, there have been numerous reports associating risk factors including systemic lupus erythematosus (SLE) with the disease. The risk of ON for SLE patients is believed to be a result of both the SLE disease state itself and the concomitant use of corticosteroids. The objective of osteonecrosis treatment is typically to halt progression or delay the onset of end-stage arthritis that may require a total joint arthroplasty (TJA). Joint-preserving procedures are attempted for pre-collapse and some post-collapse lesions. After severe subchondral collapse has occurred, TJA is often necessary to relieve pain. The purpose of this article is to draw attention to recent evidence regarding several treatment options for the management of SLE-associated ON, including lesion observation, medication, joint-preserving techniques, and TJA.

引用

页数：9

共 97 条

[1] Osteonecrosis in patients with SLE [J].