Depression and cardiovascular disease: a clinical review

被引:935
作者
Hare, David L. [1 ,2 ]
Toukhsati, Samia R. [2 ]
Johansson, Peter [3 ,4 ]
Jaarsma, Tiny [3 ,4 ]
机构
[1] Univ Melbourne, Dept Med, Heidelberg, Vic 3084, Australia
[2] AustinHlth, Dept Cardiol, Heidelberg, Vic 3084, Australia
[3] Linkoping Univ, Fac Hlth Sci, Dept Hlth & Welf Studies, S-58183 Linkoping, Sweden
[4] Linkoping Univ Hosp, Dept Cardiol, S-58185 Linkoping, Sweden
关键词
Cardiovascular disease; Depression; Quality of life; Prognosis; Screening; Management; CORONARY-HEART-DISEASE; QUALITY-OF-LIFE; ACUTE MYOCARDIAL-INFARCTION; RANDOMIZED-CONTROLLED-TRIAL; HOSPITALIZED CARDIAC PATIENTS; PERCEIVED SOCIAL SUPPORT; ARTERY-DISEASE; MANAGEMENT PROGRAM; MAJOR DEPRESSION; SEROTONIN TRANSPORTER;
D O I
10.1093/eurheartj/eht462
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiovascular disease (CVD) and depression are common. Patients with CVD have more depression than the general population. Persons with depression are more likely to eventually develop CVD and also have a higher mortality rate than the general population. Patients with CVD, who are also depressed, have a worse outcome than those patients who are not depressed. There is a graded relationship: the more severe the depression, the higher the subsequent risk of mortality and other cardiovascular events. It is possible that depression is only a marker for more severe CVD which so far cannot be detected using our currently available investigations. However, given the increased prevalence of depression in patients with CVD, a causal relationship with either CVD causing more depression or depression causing more CVD and a worse prognosis for CVD is probable. There are many possible pathogenetic mechanisms that have been described, which are plausible and that might well be important. However, whether or not there is a causal relationship, depression is the main driver of quality of life and requires prevention, detection, and management in its own right. Depression after an acute cardiac event is commonly an adjustment disorder than can improve spontaneously with comprehensive cardiac management. Additional management strategies for depressed cardiac patients include cardiac rehabilitation and exercise programmes, general support, cognitive behavioural therapy, antidepressant medication, combined approaches, and probably disease management programmes.
引用
收藏
页码:1365 / U13
页数:11
相关论文
共 109 条
[1]  
American Psychiatric Association, 2013, Diagnostic and statistical manual of mental disorders, DOI 10.1176/appi.books.9780890425596
[2]   SCREENING FOR DEPRESSION IN WELL OLDER ADULTS - EVALUATION OF A SHORT-FORM OF THE CES-D [J].
ANDRESEN, EM ;
MALMGREN, JA ;
CARTER, WB ;
PATRICK, DL .
AMERICAN JOURNAL OF PREVENTIVE MEDICINE, 1994, 10 (02) :77-84
[3]   A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I. Affective disorders [J].
Anguelova, M ;
Benkelfat, C ;
Turecki, G .
MOLECULAR PSYCHIATRY, 2003, 8 (06) :574-591
[4]  
[Anonymous], 2009, HEART LUNG CIRC
[5]   The high prevalence of multiple psychiatric disorders in stable outpatients with coronary heart disease [J].
Bankier, B ;
Januzzi, JL ;
Littman, AB .
PSYCHOSOMATIC MEDICINE, 2004, 66 (05) :645-650
[6]   Symptoms of depression, acute myocardial infarction, and total mortality in a community sample [J].
Barefoot, JC ;
Schroll, M .
CIRCULATION, 1996, 93 (11) :1976-1980
[7]   Effects of Depression and Anxiety Improvement on Adherence to Medication and Health Behaviors in Recently Hospitalized Cardiac Patients [J].
Bauer, Leah K. ;
Caro, Mario A. ;
Beach, Scott R. ;
Mastromauro, Carol A. ;
Lenihan, Emma ;
Januzzi, James L. ;
Huffman, Jeff C. .
AMERICAN JOURNAL OF CARDIOLOGY, 2012, 109 (09) :1266-1271
[8]   Cognitive Therapy: Current Status and Future Directions [J].
Beck, Aaron T. ;
Dozois, David J. A. .
ANNUAL REVIEW OF MEDICINE, VOL 62, 2011, 2011, 62 :397-409
[9]   AN INVENTORY FOR MEASURING DEPRESSION [J].
BECK, AT ;
ERBAUGH, J ;
WARD, CH ;
MOCK, J ;
MENDELSOHN, M .
ARCHIVES OF GENERAL PSYCHIATRY, 1961, 4 (06) :561-&
[10]  
Berkman LF, 2003, JAMA-J AM MED ASSOC, V289, P3106