Peripartum management of hypertension: a position paper of the ESC Council on Hypertension and the European Society of Hypertension

被引:22
作者
Cifkova, Renata [1 ,2 ,3 ]
Johnson, Mark R. [4 ]
Kahan, Thomas [5 ]
Brguljan, Jana [6 ]
Williams, Bryan [7 ]
Coca, Antonio [8 ]
Manolis, Athanasios [9 ]
Thomopoulos, Costas [10 ]
Borghi, Claudio [11 ]
Tsioufis, Costas [12 ]
Parati, Gianfranco [13 ,14 ]
Sudano, Isabella [15 ,16 ]
McManus, Richard J. [17 ]
van den Born, Bert-Jan H. [18 ,19 ]
Regitz-Zagrosek, Vera [20 ,21 ,22 ]
de Simone, Giovanni [23 ]
机构
[1] Charles Univ Prague, Fac Med 1, Ctr Cardiovasc Prevent, Videnska 800, Prague 14059 4, Czech Republic
[2] Thomayer Hosp, Videnska 800, Prague 14059 4, Czech Republic
[3] Charles Univ Prague, Fac Med 1, Dept Med 2, Prague, Czech Republic
[4] Imperial Coll, Chelsea & Westminster Hosp, Inst Reprod & Dev Biol, Sch Med, London, England
[5] Karolinska Inst, Danderyd Hosp, Dept Clin Sci, Div Cardiovasc Med, Stockholm, Sweden
[6] Univ Med Ctr Ljubljana, Med Fac, Dept Hypertens, Div Internal Med, Ljubljana, Slovenia
[7] UCL, UCL Inst Cardiovasc Sci, London, England
[8] Univ Barcelona, Hosp Clin, Dept Internal Med, Hypertens & Vasc Risk Unit, Barcelona, Spain
[9] Asklepeion Gen Hosp, Dept Cardiol, Athens, Greece
[10] Helena Venizelou Gen & Maternal Hosp, Dept Cardiol, Athens, Greece
[11] Univ Bologna, Dept Med & Surg Sci, Bologna, Italy
[12] Natl & Kapodistrian Univ Athens, Hippokration Hosp, Med Sch, Cardiol Clin 1, Athens, Greece
[13] Univ Milano Bicocca, Dept Med & Surg, Milan, Italy
[14] S Luca Hosp, Dept Cardiovasc Neural & Metab Sci, Cardiol Unit, IRCCS,Ist Auxol Italiano, Milan, Italy
[15] Univ Hosp, Dept Cardiol, Univ Heart Ctr Zurich, Zurich, Switzerland
[16] Univ Zurich, Zurich, Switzerland
[17] Univ Oxford, Nuffield Dept Primary Care Hlth Sci, Oxford, England
[18] Univ Amsterdam, Med Ctr, Dept Internal Med, Amsterdam, Netherlands
[19] Univ Amsterdam, Dept Publ Hlth, Med Ctr, Dept Vasc Med, Amsterdam, Netherlands
[20] Charite Univ Med Berlin, Berlin Inst Gender Med, Berlin, Germany
[21] Charite Univ Med Berlin, CCR, Berlin, Germany
[22] DZHK, Partner Site Berlin, Berlin, Germany
[23] Univ Naples Federico II, Hypertens Res Ctr, Dept Adv Biomed Sci, Naples, Italy
基金
英国医学研究理事会;
关键词
Pre-existing hypertension; Gestational hypertension; Pre-eclampsia; Antihypertensive drugs; Hypertensive emergency; Low dose of acetylsalicylic acid; PREGNANT-WOMEN; BLOOD-PRESSURE; MAGNESIUM-SULFATE; PREECLAMPSIA; DIAGNOSIS; ASSOCIATION; DISORDERS; RATIO; RISK; PHEOCHROMOCYTOMA;
D O I
10.1093/ehjcvp/pvz082
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hypertensive disorders are the most common medical complications in the peripartum period associated with a substantial increase in morbidity and mortality. Hypertension in the peripartum period may be due to the continuation of pre-existing or gestational hypertension, de novo development of pre-eclampsia or it may be also induced by some drugs used for analgesia or suppression of postpartum haemorrhage. Women with severe hypertension and hypertensive emergencies are at high risk of life-threatening complications, therefore, despite the lack of evidence-based data, based on expert opinion, antihypertensive treatment is recommended. Labetalol intravenously and methyldopa orally are then the two most frequently used drugs. Short-acting oral nifedipine is suggested to be used only if other drugs or iv access are not available. Induction of labour is associated with improved maternal outcome and should be advised for women with gestational hypertension or mild pre-eclampsia at 37 weeks' gestation. This position paper provides the first interdisciplinary approach to the management of hypertension in the peripartum period based on the best available evidence and expert consensus.
引用
收藏
页码:384 / 393
页数:10
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