Does Cryptosporidium parvum have a clonal population structure?

被引：21
作者：
Awad-El-Kariem, FM [1 ]
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Dept Biol, London SW7 2BB, England
来源：
PARASITOLOGY TODAY | 1999年 / 15卷 / 12期
基金：
英国惠康基金;
关键词：
D O I：
10.1016/S0169-4758(99)01567-7
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Cryptosporidiosis, the disease caused in humans by the opportunistic parasite Cryptosporidium parvum, is the result of zoonotic or anthroponotic transmission. Molecular characterization of different isolates front humans and other mammalian species has recently shown this species to be heterogeneous; this heterogeneity has been linked to the host of isolation, suggesting that the parasites causing zoonotic cryptosporidiosis and those propagated by anthroponotic transmission are genetically distinct. Here, Fatih Awad-El-Kariem provides an update on the taxonomic and epidemiological significance of these observations, and discusses evidence for and against the clonality hypothesis as a model to explain strain variation in this species.
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收藏
页码：502 / 504
页数：3
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