High-level mupirocin resistance within methicillin-resistant Staphylococcus aureus pandemic lineages

被引:37
作者
Perez-Roth, Eduardo
Lopez-Aguilar, Celeste
Alcoba-Florez, Julia
Mendez-Alvarez, Sebastian
机构
[1] Hosp Univ Ntra Sra Candelaria, Mol Biol Lab, Unidad Invest, Santa Cruz de Tenerife, Spain
[2] Hosp Univ Ntra Sra Candelaria, Unidad Microbiol, Santa Cruz de Tenerife, Spain
[3] Univ La Laguna, Dept Biol Celular & Microbiol, Santa Cruz de Tenerife, Spain
[4] CSIC, Ctr Invest Biol, Madrid, Spain
关键词
D O I
10.1128/AAC.00059-06
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The methicillin-resistant Staphylococcus aureus (MRSA) population in the Hospital Universitario Nuestra Senora de Candelaria over a 5-year period (1998 to 2002) was marked by shifts in the circulation of pandemic clones. Here, we investigated the emergence of high-level mupirocin resistance (Hi-Mup(r)). In addition to clonal spread, transfer of ileS2-carrying plasmids played a significant role in the dissemination of Hi-Mup(r) among pandemic MRSA lineages.
引用
收藏
页码:3207 / 3211
页数:5
相关论文
共 26 条