Bariatric surgery for obesity and metabolic disorders: state of the art

被引:359
作者
Nguyen, Ninh T. [1 ]
Varela, J. Esteban [2 ]
机构
[1] Univ Calif Irvine, Dept Surg, Med Ctr, 333 City Blvd West,Suite 1600, Orange, CA 92868 USA
[2] Diabet Surg Inst, 8025 Bonhomme Ave, St Louis, MO 63105 USA
关键词
ROUX-EN-Y; OPEN GASTRIC BYPASS; SLEEVE-GASTRECTOMY; WEIGHT-LOSS; FOLLOW-UP; BILIOPANCREATIC DIVERSION; MEDICAL-MANAGEMENT; AMERICAN-COLLEGE; UNITED-STATES; LIFE-STYLE;
D O I
10.1038/nrgastro.2016.170
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Obesity is one of the most important public health conditions worldwide. Bariatric surgery for severe obesity is an effective treatment that results in the improvement and remission of many obesity-related comorbidities, as well as providing sustained weight loss and improvement in quality of life. Contemporary bariatric operations include Roux-en-Y gastric bypass, sleeve gastrectomy, adjustable gastric band and the duodenal switch. The vast majority of these procedures are now performed using laparoscopic technique, the main advantages of which include rapid recovery, the reduction of postoperative pain and the reduction of wound-related complications, compared with open surgery. Contemporary bariatric surgery is now safe, with a mortality of three in 1,000 patients; however, all bariatric operations are associated with their own unique short-term and long-term nutritional and procedural-related complications. Type 2 diabetes mellitus (T2DM) is the most studied metabolic disorder associated with obesity, with data demonstrating that improvement and remission of T2DM in patients with obesity is superior after bariatric surgery compared with conventional medical therapy. Bariatric surgery is now a part of some treatment algorithms for the medical management of patients with T2DM and severe obesity. New, minimally invasive and endoscopic devices for the treatment of obesity have now been approved in the USA, which will expand the treatment options for individuals with obesity.
引用
收藏
页码:160 / 169
页数:10
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