Cancer immunity thwarted by the microbiome

被引：21

作者：

Hartmann, Nadine ^{[1
]}

Kronenberg, Mitchell ^{[1
,2
]}

机构：

[1] La Jolla Inst Allergy & Immunol, Div Dev Immunol, La Jolla, CA 92037 USA

[2] Univ Calif San Diego, Div Biol, La Jolla, CA 92037 USA

来源：

SCIENCE | 2018年 / 360卷 / 6391期

关键词：

BILE-ACIDS; T-CELLS; TOLERANCE; LIVER;

D O I：

10.1126/science.aat8289

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

[No abstract available]

引用

页码：858 / 859

页数：2

共 14 条

[1] Bile Acids Induce Inflammatory Genes in Hepatocytes A Novel Mechanism of Inflammation during Obstructive Cholestasis [J].

Allen, Katryn ;

Jaeschke, Hartmut ;

Copple, Bryan L. .

AMERICAN JOURNAL OF PATHOLOGY, 2011, 178 (01) :175-186

[2] Activation and Function of iNKT and MAIT Cells [J].

Chandra, Shilpi ;

Kronenberg, Mitchell .

ADVANCES IN IMMUNOLOGY, VOL 127, 2015, 127 :145-201

[3] A critical role for natural killer T cells in immunosurveillance of methylcholanthrene-induced sarcomas [J].

Crowe, NY ;

Smyth, MJ ;

Godfrey, DI .

JOURNAL OF EXPERIMENTAL MEDICINE, 2002, 196 (01) :119-127

[4] Immunity, tolerance and autoimmunity in the liver: A comprehensive review [J].

Doherty, Derek G. .

JOURNAL OF AUTOIMMUNITY, 2016, 66 :60-75

[5] Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells [J].

Ma, Chi ;

Han, Miaojun ;

Heinrich, Bernd ;

Fu, Qiong ;

Zhang, Qianfei ;

Sandhu, Milan ;

Agdashian, David ;

Terabe, Masaki ;

Berzofsky, Jay A. ;

Fako, Valerie ;

Ritz, Thomas ;

Longerich, Thomas ;

Theriot, Casey M. ;

McCulloch, John A. ;

Roy, Soumen ;

Yuan, Wuxing ;

Thovarai, Vishal ;

Sen, Shurjo K. ;

Ruchirawat, Mathuros ;

Korangy, Firouzeh ;

Wang, Xin Wei ;

Trinchieri, Giorgio ;

Greten, Tim F. .

SCIENCE, 2018, 360 (6391)

[6] The Contribution of Non-Professional Antigen-Presenting Cells to immunity and Tolerance in the Liver [J].

Mehrfeld, Christina ;

Zenner, Steven ;

Kornek, Miroslaw ;

Lukacs-Kornek, Veronika .

FRONTIERS IN IMMUNOLOGY, 2018, 9

[7] Invariant NKT cells amplify the innate immune response to lipopolysalecharide [J].

Nagarajan, Niranjana A. ;

Kronenberg, Mitchell .

JOURNAL OF IMMUNOLOGY, 2007, 178 (05) :2706-2713

[8] Bile acids and the gut microbiome [J].

Ridlon, Jason M. ;

Kang, Dae J. ;

Hylemon, Phillip B. ;

Bajaj, Jasmohan S. .

CURRENT OPINION IN GASTROENTEROLOGY, 2014, 30 (03) :332-338

[9] Bile acid receptors as targets for drug development [J].

Schaap, Frank G. ;

Trauner, Michael ;

Jansen, Peter L. M. .

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2014, 11 (01) :55-67

[10] The microbiome and cancer [J].

Schwabe, Robert F. ;

Jobin, Christian .

NATURE REVIEWS CANCER, 2013, 13 (11) :800-812

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