Structures of KOD and 9°N DNA Polymerases Complexed with Primer Template Duplex

被引:47
作者
Bergen, Konrad [1 ,2 ]
Betz, Karin [1 ,2 ]
Welte, Wolfram [1 ,2 ]
Diederichs, Kay [1 ,2 ]
Marx, Andreas [1 ,2 ]
机构
[1] Univ Konstanz, Konstanz Res Sch Chem Biol, Dept Chem, D-78457 Constance, Germany
[2] Univ Konstanz, Konstanz Res Sch Chem Biol, Dept Biol, D-78457 Constance, Germany
关键词
DNA replication; family B; modified nucleotide; polymerase chain reaction; X-ray structure; X-RAY CRYSTALLOGRAPHY; CRYSTAL-STRUCTURE; NUCLEOSIDE TRIPHOSPHATES; ENZYMATIC INCORPORATION; B-DNA; NUCLEOTIDE INCORPORATION; LABELED NUCLEOTIDES; FUNCTIONALIZED DNA; DEAMINATED BASES; NUCLEIC-ACIDS;
D O I
10.1002/cbic.201300175
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:1058 / 1062
页数:5
相关论文
共 67 条
[1]   Incorporation of reporter-labeled nucleotides by DNA polymerases [J].
Anderson, JP ;
Angerer, B ;
Loeb, LA .
BIOTECHNIQUES, 2005, 38 (02) :257-264
[2]  
[Anonymous], 2009, ANGEW CHEM, V121, P2710
[3]  
Baccaro A., 2012, ANGEW CHEM, V124, P260
[4]   Barcoded Nucleotides [J].
Baccaro, Anna ;
Steck, Anna-Lena ;
Marx, Andreas .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 51 (01) :254-257
[5]   Accurate whole human genome sequencing using reversible terminator chemistry [J].
Bentley, David R. ;
Balasubramanian, Shankar ;
Swerdlow, Harold P. ;
Smith, Geoffrey P. ;
Milton, John ;
Brown, Clive G. ;
Hall, Kevin P. ;
Evers, Dirk J. ;
Barnes, Colin L. ;
Bignell, Helen R. ;
Boutell, Jonathan M. ;
Bryant, Jason ;
Carter, Richard J. ;
Cheetham, R. Keira ;
Cox, Anthony J. ;
Ellis, Darren J. ;
Flatbush, Michael R. ;
Gormley, Niall A. ;
Humphray, Sean J. ;
Irving, Leslie J. ;
Karbelashvili, Mirian S. ;
Kirk, Scott M. ;
Li, Heng ;
Liu, Xiaohai ;
Maisinger, Klaus S. ;
Murray, Lisa J. ;
Obradovic, Bojan ;
Ost, Tobias ;
Parkinson, Michael L. ;
Pratt, Mark R. ;
Rasolonjatovo, Isabelle M. J. ;
Reed, Mark T. ;
Rigatti, Roberto ;
Rodighiero, Chiara ;
Ross, Mark T. ;
Sabot, Andrea ;
Sankar, Subramanian V. ;
Scally, Aylwyn ;
Schroth, Gary P. ;
Smith, Mark E. ;
Smith, Vincent P. ;
Spiridou, Anastassia ;
Torrance, Peta E. ;
Tzonev, Svilen S. ;
Vermaas, Eric H. ;
Walter, Klaudia ;
Wu, Xiaolin ;
Zhang, Lu ;
Alam, Mohammed D. ;
Anastasi, Carole .
NATURE, 2008, 456 (7218) :53-59
[6]   Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates [J].
Bergen, Konrad ;
Steck, Anna-Lena ;
Struett, Stefan ;
Baccaro, Anna ;
Welte, Wolfram ;
Diederichs, Kay ;
Marx, Andreas .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (29) :11840-11843
[7]  
Betz K., 2010, ANGEW CHEM, V122, P5308
[8]  
Betz K, 2012, NAT CHEM BIOL, V8, P612, DOI [10.1038/NCHEMBIO.966, 10.1038/nchembio.966]
[9]   Structures of DNA Polymerases Caught Processing Size-Augmented Nucleotide Probes [J].
Betz, Karin ;
Streckenbach, Frank ;
Schnur, Andreas ;
Exner, Thomas ;
Welte, Wolfram ;
Diederichs, Kay ;
Marx, Andreas .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (30) :5181-5184
[10]   COMPILATION, ALIGNMENT, AND PHYLOGENETIC-RELATIONSHIPS OF DNA-POLYMERASES [J].
BRAITHWAITE, DK ;
ITO, J .
NUCLEIC ACIDS RESEARCH, 1993, 21 (04) :787-802